男性不育是较为常见的病症,约4%的男性受到不育的困扰。男性原发性不育与男性生殖相关基因的缺陷有密切关系。近年来,国内外发表了大量文献展示了新发现的与男性生殖相关的基因。刘美玲等[1]在采用抑制性消减杂交技术(SSH)筛选大鼠精原细胞与精母细胞差异表达基因过程中,发现了 Male infertility is a more common condition, about 4% of men suffer from infertility. Male primary infertility and male reproductive related gene defects are closely related. In recent years, a large number of literatures have been published both at home and abroad to show the newly discovered genes related to male reproduction. Liu Meiling et al [1] in the suppression subtractive hybridization (SSH) screening spermatogonia and spermatogonial differentially expressed genes found that