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目的 :评价溴敌隆防制家栖鼠的效果。方法 :实验室毒力测定和摄食试验 ;现场灭鼠效果考核。结果 :(1)溴敌隆对大白鼠的急性LD50 和回归方程分别为 0 .86 (0 .80～ 0 .92 )mg/kg和^Y =6 .11+17.0 7x ,慢性LD50 和回归方程分别为 0 .16 (0 .15～ 0 .18)× 5mg/kg和 ^Y =15.80 +13.72x ;对小白鼠的急性LD50 和回归方程分别为 1.19(1.0 1～ 1.2 7)mg/kg和 ^Y =4 .4 6 +9.6 9x ,慢性LD50 和回归方程分别为 0 .2 2 (0 .2 0～ 0 .2 5)× 5mg/kg和 ^Y =10 .57+8.6 0x。 (2 ) 0 .0 0 5%溴敌隆毒铒对大白鼠和小白鼠无选择和有选择摄食试验 ,都达到 10 0 %毒杀率 ;有选择试验的摄食系数分别为 0 .95和 1.4 4。 (3)现场试验 ,投毒饵 7d灭鼠率 6 6 % ,2 1d和 35d灭鼠率分别为 84 %和 95%。结论 :溴敌隆对两种家栖鼠毒性强 ,适口性好 ,毒效高。
Objective: To evaluate the effect of bromadiolone against domestic rats. Methods: Laboratory toxicity test and feeding test; field rodent control test. Results: (1) The acute LD50 and regression equation of bromadiolone in rats were 0.86 (0.80 ~ 0.92) mg / kg and ^ Y = 6.11 ± 17.0 7x, respectively. Chronic LD50 and regression equation (0.15 ~ 0.18) × 5mg / kg and ^ Y = 15.80 + 13.72x respectively; the acute LD50 and regression equation of the mice were 1.19 (1.01 ~ 1.2 7) mg / kg and ^ Y = 4 .4 6 +9.6 9x, the chronic LD50 and the regression equation were respectively 0.2 2.2 (0.2-2.5) × 5 mg / kg and ^ Y = 10.57 + 8.6 ×. (2) 0. 0 0 5% Erlotinib erbium in rats and mice selective feeding and selective feeding tests, have reached 100% poisoning rate; selective test of food intake coefficients were 0.95 and 1.4 4. (3) In field tests, the rate of rodent infestation was 66% at 7 days and 84% and 95% at 21d and 35d, respectively. Conclusion: Bromadiolone is toxic to both domestic animals and has good palatability and high toxicity.