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目的对比PET-CT及CT在周围型非小细胞肺癌N分期的准确度,评价其在纵隔淋巴结清扫中的价值。方法回顾分析得到最终病理确诊的34例周围型非小细胞肺癌病例,以病理结果对PET-CT和CT结果进行统计学分析评价,计算两者灵敏度、特异度、准确度、阳性预测值与阴性预测值。结果 34例患者N分期中,PET-CT的灵敏度、特异度、准确度、阳性预测值与阴性预测值分别为93.3%、78.9%、85.3%、77.8%、93.8%,而对应CT分别为63.6%、69.6%、67.6%、50.0%、80.0%,两者有统计学差异(P<0.05)。结论 PET-CT在周围型非小细胞肺癌N分期上优于CT,其在评估纵隔淋巴结转移情况准确率较高;对周围型非小细胞肺癌尤其PET-CT临床分期为N0期肺癌,对FDG摄取阴性的淋巴结可选择性清扫。
Objective To compare the accuracy of PET-CT and CT in N staging of peripheral non-small cell lung cancer (NSCLC) and to evaluate its value in dissecting lymph nodes. Methods A retrospective analysis of the final pathological diagnosis of 34 cases of peripheral non-small cell lung cancer cases, the pathological results of PET-CT and CT results were statistically analyzed to evaluate the sensitivity, specificity, accuracy, positive predictive value and negative Predictive value. Results The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of PET-CT were 93.3%, 78.9%, 85.3%, 77.8% and 93.8% respectively in 34 patients with N staging, while the corresponding CT values were 63.6 %, 69.6%, 67.6%, 50.0% and 80.0%, respectively (P <0.05). Conclusions PET-CT is superior to CT in peripheral staging of non-small cell lung cancer and its accuracy in assessing mediastinal lymph node metastasis. PET-CT in peripheral non-small cell lung cancer, especially in clinical stage N0 lung cancer, FDG Ingestion of negative lymph nodes can be selectively cleaned.