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目的了解上海市黄浦区自然人群流感抗体水平,为制定防制策略提供依据。方法于2013年10月对黄浦区居民随机抽样414人,收集血清,采用血凝抑制试验检测流感HI抗体,统计分析抗体水平。结果全人群流感抗体阳性率以流感病毒甲3型(AH3)、乙型BY(BY)及甲型H1N1型(AH1N1)为高,均≥95%,乙型BV(BV)、甲1型(AH1)≥70%,甲型H5N1(AH5N1)、甲型H7N9(AH7N9)、甲型H9N2(AH9N2)均<1%。几何平均滴度AH3最高,为1:287;AH1N1、BY其次,分别为1:185、1:170,BV、AH1较低,分别为1:45、1:23,AH5N1、AH7N9、AH9N2均为1:5。0~4岁和≥60岁人群抗体滴度相对较低,5~14、15~24、25~60岁组较高。结论黄浦区居民流感抗体水平以AH3最高,AH1N1、BY其次,BV、AH1较低;幼儿和老人抗体水平较低。应适度按排流感疫苗的预防接种工作。
Objective To understand the level of influenza antibodies in the natural population in Huangpu District of Shanghai and provide evidence for the development of control strategies. Methods In October 2013, 414 residents of Huangpu District were randomized to receive serum HI. HI antibody was detected by hemagglutination inhibition test and antibody levels were statistically analyzed. Results The positive rate of influenza antibody in the whole population was higher than that of influenza virus type A (AH3), type BY (BY) and type A H1N1 (all ≥95%), type BV (BV), type A AH1) ≥70%, H5N1 (AH5N1), H7N9 (AH7N9) and H9N2 (AH9N2) were all less than 1%. The average geometric mean titer (AH3) was 1: 287; AH1N1 and BY followed by 1: 185, 1: 170 and BV, respectively, with lower AH1 values of 1:45 and 1:23, respectively, and AH5N1, AH7N9 and AH9N2 1: The titer of antibody in 5.0 ~ 4 years old and ≥60 years old people is relatively low, 5 ~ 14,15 ~ 24,25 ~ 60 years old group is higher. Conclusions The level of influenza antibody in Huangpu district is the highest with AH3, followed by AH1N1 and BY, while BV and AH1 are lower. The level of antibody in young children and the elderly is lower. Vaccination should be appropriately flu vaccination vaccination.