本文应用国产法莫替丁每日口服40mg 治疗消化性溃疡31例,对胃、十二指肠溃疡四周总愈合率为84.6%,与国内报道相似。对照组雷尼替丁治疗34例,对胃、十二指肠溃疡四周总愈合率为77.8%。两组无显著性差别(P>0.05)。但对消除溃疡疼痛及消化道症状治疗组优于对照组(P≤0.05),而且副作用少。作为消化性溃疡的治疗药物,法莫替丁是一种安全可靠有效的新型 H_2-受体拮抗剂,值得临床推广应用。 In this paper, domestic famotidine 40 mg daily oral administration of peptic ulcer in 31 cases, the gastric and duodenal ulcer around the total healing rate was 84.6%, similar to the domestic reports. The control group ranitidine treatment of 34 cases of stomach, duodenal ulcer around the total healing rate of 77.8%. There was no significant difference between the two groups (P> 0.05). But for the treatment of ulcer pain and gastrointestinal symptoms than the control group (P≤0.05), and less side effects. As a therapeutic drug for peptic ulcer, famotidine is a safe, reliable and effective new H 2 -receptor antagonist, worthy of clinical application.