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我们用单向琼脂扩散试验．对影响纤维结合蛋白测定的几种因素进行了探讨．并以最佳条件测定了不同年龄组健康人及几种疾病患者血浆纤维结合蛋白水平，结果表明．新生儿血浆纤维结合蛋白水平显著低于各年龄组人群．而幼儿组又高于成年和老年组。烧伤、肝硬化、Ⅱ型糖尿病及小儿肺炎患者血浆纤维结合蛋白水平明显低于相应年龄组对照．而甲亢患者的血浆纤维结合蛋白水平却明显高于对照。
We used one-way agar diffusion test. Several factors that affect the determination of fibronectin were explored. The optimal conditions for the determination of plasma fibronectin levels in healthy people and several diseases in different age groups were obtained. Neonatal plasma fibronectin levels were significantly lower in all age groups. The group of children is higher than the group of adults and seniors. Burn, cirrhosis, type II diabetes and pneumonia in patients with plasma fibronectin levels were significantly lower than the corresponding age group control. Hyperthyroidism patients with plasma fibronectin levels were significantly higher than the control.