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目的:探讨平糖益肾汤联合厄贝沙坦治疗早期糖尿病肾病患者的疗效。方法:选择2014年3月—2015年3月来我院就诊的80例早期糖尿病肾病患者,随机数字表法分为对照组和观察组。对照组患者仅使用厄贝沙坦治疗,观察组患者给予平糖益肾汤联合厄贝沙坦治疗。治疗12周后,分析对比两组患者的空腹血糖、糖化血红蛋白、尿蛋白的肾功能情况,并对比治疗效果。结果:观察组患者的总有效率明显高于对照组,差异有统计学意义(P<0.05)。治疗后两组患者的空腹血糖、糖化血红蛋白、尿蛋白均有所改善,与治疗前相比有统计学意义(P<0.05,P<0.01)。与对照组相比,观察组的血糖、糖化血红蛋白、尿蛋白均明显改善,结果有统计学意义(P<0.01)。结论:平糖益肾汤联合厄贝沙坦治疗早期糖尿病肾病,能够有效的降低血糖、降低尿蛋白的水平,且能够改善肾功能情况,能够有效的抑制早期糖尿病肾病的发展,值得在临床上推广使用。
Objective: To investigate the efficacy of Ping Tang Yishen Decoction combined with irbesartan in the treatment of patients with early diabetic nephropathy. Methods: Eighty patients with early diabetic nephropathy who visited our hospital from March 2014 to March 2015 were randomly divided into control group and observation group. The control group of patients treated with irbesartan only, the observation group of patients given Ping Tang Yishen Tang combined irbesartan treatment. After 12 weeks of treatment, the fasting blood glucose, glycosylated hemoglobin and urinary protein in two groups were analyzed and compared, and the therapeutic effects were compared. Results: The total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05). After treatment, fasting blood glucose, glycosylated hemoglobin and urine protein in both groups improved, with statistical significance (P <0.05, P <0.01). Compared with the control group, the observation group of blood glucose, glycosylated hemoglobin, urine protein were significantly improved, the results were statistically significant (P <0.01). Conclusion: The treatment of early diabetic nephropathy with Ping Tang Yishen Decoction combined with irbesartan can effectively lower blood glucose, reduce the level of urinary protein, and can improve the renal function, which can effectively inhibit the development of early diabetic nephropathy, which deserves clinical Promote use.