为了探讨无不育史的精索静脉曲张患者在精索曲张静脉结扎术后精液参数是否获得改善,以及与激素或生化标志物(尤其是一氧化氮)的关联性。Rodriguez Pena M等收集202例左侧精索静脉曲张Ⅱ或Ⅲ度患者的精液标本。用Griess技术测定精浆中一氧化氮水平,应用超声测定双侧睾丸体积,并进行血清激素水平测定。结果发现精子密度正常或轻度度减少的患者,术后精子密度显著升高,但中度和重度少精患者的精子密 To investigate if semen parameters improved after varicocele ligation in infertile patients with varicocele and their association with hormones or biochemical markers, especially nitric oxide. Rodriguez Pena M and other 202 cases of left varicocele Ⅱ or Ⅲ degree semen samples were collected. The level of nitric oxide in seminal plasma was determined by Griess technique. The volume of bilateral testes was measured by ultrasound and serum hormone levels were measured. The results showed that sperm density was normal or mild degree of reduction in patients with postoperative sperm density was significantly increased, but moderate and severe oligospermia in patients with sperm dense