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DMRT1基因编码的保守转录因子对性腺功能发挥具有重要的作用。在家禽中,DMRT1基因定位于Z染色体上,最适合用于研究家禽性腺分化的调控因子。先前的研究显示在性别分化期间敲除该基因会诱导雄性鸡胚性腺出现雌性化,因此这个基因为鸡的睾丸正常发育所必需,但它是否足以诱导睾丸分化则不甚清楚。澳大利亚、美国、日本3个国家的科研人员联合进行的一项研究发现,过量表达的DMRT1可诱导
The DMRT1 gene encodes a conserved transcription factor that plays an important role in gonadal function. In poultry, the DMRT1 gene is located on the Z chromosome and is most suitable for studying regulatory factors of gonadal differentiation in poultry. Previous studies have shown that knocking out this gene during sex differentiation induces gonadal sex in male chicken embryos, so this gene is necessary for the normal development of the testes in chickens, but it is unclear whether it is sufficient to induce testicular differentiation. A study jointly conducted by researchers from three countries in Australia, the United States and Japan found that DMRT1 overexpressed