论文部分内容阅读
目的:观察参芪降糖经验方联合常规疗法治疗2型糖尿病性胃肠病患者的临床效果。方法:纳入80例2型糖尿病性胃肠病患者,随机分为对照组和治疗组各40例。对照组在饮食控制、运动锻炼基础上服用盐酸二甲双胍片联合西沙比利片治疗;治疗组则在对照组基础上加用参芪降糖经验方内服治之。2组均以2周为1疗程,连续治疗4疗程。观察2组的降糖效果及胃肠功能变化。结果:降糖疗效总有效率治疗组90.0%,对照组70.0%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组葡萄糖负荷后2 h血糖(P2hBG)、糖化血红蛋白(HbA1c)、空腹血糖(FBG)均较治疗前下降,差异均有统计学意义(P<0.05);治疗组3项指标值均低于对照组患者,差异均有统计学意义(P<0.05)。治疗组餐后不适、早饱、厌食、恶心、便秘等中医证候积分均低于对照组,差异均有统计学意义(P<0.05)。结论:参芪降糖经验方联合常规疗法对2型糖尿病性胃肠病患者具有良好的降糖效果,能显著改善患者的胃肠功能,凸显出中西医结合治疗糖尿病及其并发症的优势与特色,值得临床推广运用。
Objective: To observe the clinical effect of Shenqi Hypoglycemic prescription combined with conventional therapy in the treatment of type 2 diabetic gastrointestinal disease. Methods: Eighty patients with type 2 diabetic gastrointestinal disease were enrolled and randomly divided into control group and treatment group with 40 cases each. The control group took metformin hydrochloride tablets combined with cisapride tablets on the basis of diet control and exercise training. The treatment group was treated with Shenqi hypoglycemic prescription on the basis of the control group. 2 groups were 2 weeks for a course of treatment, continuous treatment 4 courses. The hypoglycemic effect and gastrointestinal function of the two groups were observed. Results: The total effective rate of hypoglycemic treatment was 90.0% in the treatment group and 70.0% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the blood glucose (P2hBG), HbA1c and fasting blood glucose (FBG) in 2 groups after 2h glucose loading decreased compared with those before treatment, the differences were statistically significant (P <0.05) Were lower than the control group patients, the difference was statistically significant (P <0.05). The scores of TCM syndromes such as premature senility, anorexia, nausea and constipation in the treatment group were lower than those in the control group, with significant differences (P <0.05). Conclusion: Shenqi Hypoglycemic prescription combined with conventional therapy has a good hypoglycemic effect on patients with type 2 diabetic gastrointestinal disease, can significantly improve the gastrointestinal function of patients, highlights the advantages of combining traditional Chinese and Western medicine in the treatment of diabetes mellitus and its complications Characteristics, it is worth to promote clinical use.