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应用分子生物学技术——多聚酶链反应(Polymerase Chain Reaction,PCR)对临床和组织学确诊的女性生殖道尖锐湿疣(湿疣)、部分湿疣病人的内裤拭子和正常妇女阴道壁拭子的人类乳头瘤病毒DNA(HPV-DNA)进行检测。结果显示:尖锐湿疣病人绝大部分是由HPV感染所致(98.25％),湿疣病人的内裤拭子HPV-DNA阳性率为73.68％,正常妇女阴道壁拭子HPV-DNA阳性率为54.00％。结果提示:性交不是尖锐湿疣传播的唯一途径,病人污染物的接触和生殖道HPV的亚临床感染是尖锐湿疣传播中不可忽视的途径。
Polymerase Chain Reaction (PCR) was applied to detect the clinical and histologically confirmed female reproductive tract condyloma acuminata (genital warts), the panty swabs of some genital warts and the vaginal wall swabs of normal women Tumor virus DNA (HPV-DNA) was tested. The results showed that the majority of patients with condyloma acuminatum were caused by HPV infection (98.25%). The HPV-DNA positive rate of psoriasis patients was 73.68%. The positive rate of HPV-DNA was 54.00%. The results suggest that sexual intercourse is not the only way to transmit condyloma acuminatum. Patient contact with contaminants and subclinical HPV infection in the reproductive tract are indispensable pathways for condyloma acuminatum.