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目的分析该院2型糖尿病患者的用药情况、趋势及影响因素,为指导临床合理用药提供参考。方法对医院门诊西药房2型糖尿病患者342例药物使用情况进行回顾性调查研究,比较不同类别糖尿病治疗药物的使用构成比,对患者进行自制问卷调查,分析找出用药情况的影响因素。结果 2014年该院糖尿病治疗药物中使用频率前3位的是(人)胰岛素、吡格列酮及格列吡嗪,2015年使用频率前3位的是胰岛素类似物、(人)胰岛素及吡格列酮。文化程度、体质量指数、饮食控制、用药种类、疾病认知程度、家属关注程度等均在一定程度上影响2型糖尿病患者的用药依从性。结论 (人)胰岛素、胰岛素类似物等胰岛素抑制剂是临床上应用最为广泛的糖尿病治疗药物;提高患者用药依从性,应从合理改善患者的体质量指数、饮食控制、用药种类、疾病认知程度及家属关注程度入手。
Objective To analyze the medication status, trend and influencing factors of patients with type 2 diabetes mellitus in our hospital and provide references for clinical rational drug use. Methods A retrospective study of 342 patients with type 2 diabetes mellitus in the outpatient clinic of western medicine hospital was conducted to compare the using proportions of different types of diabetes mellitus. The patients were surveyed by questionnaire to find out the influencing factors. Results In 2014, the first three most frequently used drugs for diabetes treatment in the hospital were (human) insulin, pioglitazone and glipizide. In the top three in 2015, insulin analogs, (human) insulin and pioglitazone were used. The level of education, body mass index, diet control, the type of medication, the degree of disease cognition, the degree of family members’ attention and so on all affected the drug compliance of type 2 diabetic patients to a certain extent. Conclusions Insulin inhibitors such as (human) insulin and insulin analogs are the most widely used drugs for the treatment of diabetes. To improve the compliance of patients should be based on a reasonable improvement of body mass index, diet control, medication type, disease awareness and Family members concerned about the degree of start.