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采用双抗体夹心酶联免疫吸附试验(ELISA)检测再生障碍性贫血患者应用补肾泻肝方治疗前中后的血清sIL-2R水平,分析其与疗效的关系。结果:有效病例治疗前中后的血清sIL-2R值有明显差异(P<001~005),且明显高于无效组(P<001~005),显示有效组临床疗效与血清sIL-2R值变化明显相关。结论:动态检测血清sIL-2R水平可望成为监测再生障碍性贫血临床疗效的指标之一。
The level of serum sIL-2R in patients with aplastic anemia treated with Bu Shen Xie Gan Fang before and after treatment was detected by double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) and its relationship with efficacy was analyzed. Results: The serum levels of sIL-2R in effective cases were significantly different before and after treatment (P<001~005), and were significantly higher than those in the ineffective group (P<001~005), indicating effective groups. Clinical efficacy was significantly related to changes in serum sIL-2R. Conclusion: Dynamic detection of serum sIL-2R level is expected to be one of the indicators for monitoring the clinical efficacy of aplastic anemia.