肝素钠生物测定方法有多种,所使用的血凝材料各国药典规定不同。如美国药典规定绵羊血浆,日本药局方规定牛全血,英国药典规定牛全血和绵羊血浆,我国药典规定兔全血等。随着对肝素钠生物测定法血凝材料的研究,能否把猪血浆作为法定血凝材料,一直受到药检工作者的重视。 Heparin sodium biological determination of a variety of methods, the use of blood coagulation material Pharmacopoeia different countries. Such as the United States Pharmacopoeia provisions of sheep plasma, the Japanese Pharmacopoeia prescription cattle whole blood, the British Pharmacopoeia provides cattle whole blood and sheep plasma, China’s Pharmacopoeia provides whole blood rabbit and so on. With the heparin sodium bioassay of hemagglutination material research, whether the pig plasma as a statutory hemagglutinating material, has been the focus of drug testing workers.