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目的: 探讨海螵蛸与其近似基原品种的鉴别特征.方法: 参考已有生药鉴别,以及乌贼科权威分类学文献,在对来源准确实物标本观察和记录的基础上,结合体式显微及成像技术,对海螵蛸药典品——金乌贼和无针乌贼,与近似基原品种——白斑乌贼和目乌贼,进行了较为深入的形态鉴别研究,归纳总结了适用于药材和饮片的鉴别特征,并制定了检索表.结果: 海螵蛸《药典》品与其近似基原品种在背面的纵肋、腹面的纵槽、横层纹的峰形等形态特征上存在明显差异.结论: 通过本次实验研究,补充完善了海螵蛸与其近似基原品种的重要鉴别特征,为海螵蛸的监督检验和标准制订提供了参考.“,”Objective: To investigate the identification characteristics of cuttlebone and its analog species. Methods: With reference to the identification of existing crude drugs and the authoritative taxonomic literature on Sepiidae, an in-depth morphological identification study was performed to distinguish Sepia esculenta and Sepiella maindroni listed in Chinese Pharmacopoeia from the analog species Sepia latimanus and Sepia aculeata,based on the observation and recording of specimens with accurate sources combined with stereomicroscopy and imaging techniques. The identification characteristics applicable to medicinal materials and decoction pieces were summarized and a search form was developed. Results: There were significant differences between the species of cuttlebone listed in Chinese Pharmacopoeia and the analog species of cuttlebone in the morphological characteristics of the longitudinal ribs on the back,the longitudinal grooves on the ventral surface, and the peak shape of the transverse layer. Conclusion: This experimental study supplements and perfects the identification characteristics of cuttlebone and its analog species and provides a reference for supervision,inspection, and development of related standards for cuttlebone.