论文部分内容阅读
目的探讨激素药物致类固醇肌病的发病特点、发病机制及治疗措施。方法对2015年10月20日入院治疗的1例使用激素致类固醇肌病患者的临床资料进行回顾性分析。结果患者因“左下肢疼痛伴萎缩20年,复发伴四肢肌肉萎缩6个月”入院。既往诊断为“坐骨神经痛”后患者私自滥用激素(曲安奈德)治疗后出现四肢肌肉乏力、萎缩,四肢近端肌力5-级,肌酸激酶53 U/L,神经肌电图检查提示四肢神经源性损害,考虑类固醇肌病,立即停用激素,后患者症状逐渐好转。结论类固醇肌病发病与糖皮质激素滥用密切相关,规范使用激素并及时发现激素使用的并发症类固醇肌病,并停用糖皮质激素,是避免发病和改善预后最重要的措施。
Objective To investigate the characteristics, pathogenesis and treatment of steroid myopathy induced by hormonal drugs. Methods The clinical data of 1 patient who had steroid-induced steroid myopathy treated on October 20, 2015 were retrospectively analyzed. Results Patients with “left lower extremity pain with atrophy for 20 years, relapse with limb atrophy 6 months ” admission. Previous diagnosis of “sciatica” after the patient abuse of hormones (triamcinolone acetonide) after treatment of limb muscle weakness, atrophy, proximal extremity muscle 5-grade, creatine kinase 53 U / L, neuromuscular examination Prompt neurogenic damage limbs, consider steroid myopathy, immediately stop using hormones, the patient’s symptoms gradually improved. Conclusion The incidence of steroid myopathy and glucocorticoid abuse are closely related to regulate the use of hormones and timely detection of hormonal complications of steroid myopathy and disable glucocorticoid is to prevent the onset and improve prognosis of the most important measures.