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青霉素钾(以下简称pen-K)在使用中存在两大缺点:过敏和疼痛,其过敏问题已由卫生部药品生物制品检定所研究,提出系杂质引起;但疼痛迄今尚无良法克服,不仅儿童惧怕,成人也难以忍受。虽然有苯甲醇作无痛溶媒,但常引起结块影响吸收,据报道甚至引起16例婴儿死亡。文献虽提出0.15~0.5%的盐酸(?)多卡因,可减轻疼痛在97.2%以上,文献也提出0.2%盐酸利多卡因为有效抑痛浓度。但动物体内各项指标及临床实验未见报
Penicillin potassium (hereinafter referred to as pen-K) in the use of the existence of two major drawbacks: allergies and pain, allergy problems have been studied by the Ministry of Health Drug and Biological Products, made of impurities caused; but so far no pain to overcome the pain, not only children Fear, adults are unbearable. Although benzyl alcohol is an indolent vehicle, it often causes agglomeration to affect absorption and is reported to cause even 16 infant deaths. Although the literature proposed 0.15 ~ 0.5% hydrochloric acid (?) Doxorubicin, can reduce pain over 97.2%, the literature also proposed 0.2% lidocaine hydrochloride effective inhibitory concentration. However, various indicators of animals and clinical trials have not been reported