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目的探讨高同型半胱氨酸(Hcy)血症对急性缺血性脑卒中患者近期疗效和生活质量的影响。方法选取2014年1月至2016年2月该院进行治疗的急性缺血性脑卒中患者120例作为研究对象,并根据血浆Hcy水平分为高Hcy组(50例)和正常Hcy组(70例),比较两组近期治疗效果、生活质量评分及随访期间血管事件再发率。结果高Hcy组临床治疗总有效率、生活质量各维度评分及随访期血管疾病再发率明显低于正常Hcy组,差异有统计学意义(P<0.05)。结论高Hcy血症是急性缺血性脑卒中预后不良的一个重要因素。
Objective To investigate the effect of hyperhomocysteinemia on short-term efficacy and quality of life in patients with acute ischemic stroke. Methods A total of 120 acute ischemic stroke patients treated in our hospital from January 2014 to February 2016 were selected as subjects and divided into high Hcy group (50 cases) and normal Hcy group (70 cases ), The two groups of recent treatment, quality of life scores and follow-up of vascular event recurrence rate. Results The total effective rate of clinical treatment, the quality of life scores and the follow-up of vascular disease recurrence in high-Hcy group were significantly lower than those in normal Hcy group (P <0.05). Conclusions Hyperhomocysteinemia is an important factor in the poor prognosis of acute ischemic stroke.