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目的 :探讨血清 CA12 5在肺癌诊断和疗效观察中的价值。方法 :检测 87例肺癌治疗前后血清 CA12 5水平。结果 :以 CA12 5 >35 U/m L 为阳性界值 ,CA12 5对肺癌的诊断率为 4 7.1% ,其阳性检出率分别是 :鳞癌 4 1.7% ,腺癌 4 3.3% ,未分化癌 6 1.9% ,未分化癌与鳞癌 CA12 5水平比较 ,有显著差异 (P<0 .0 5 )。CA12 5水平还与临床分期有关 , b、 期明显高于 b、 a、 b、 a 期 (P<0 .0 5 )。结论 :血清 CA12 5水平对肺癌诊断具有一定的价值 ,是临床分期、疗效观察及预后判断的重要参考指标。
Objective: To investigate the value of serum CA12 5 in the diagnosis and treatment of lung cancer. Methods: The levels of serum CA12 5 in 87 patients with lung cancer before and after treatment were measured. Results: The positive detection rate of CA12 5 to lung cancer was 47.1% with CA12 5> 35 U / m L as the positive cutoff value. The positive detection rates were 4 1.7% for squamous cell carcinoma, 3.3% for adenocarcinoma, undifferentiated Cancer 6 1.9%, undifferentiated carcinoma and squamous cell carcinoma CA12 5 levels, there was a significant difference (P <0.05). The level of CA12 5 was also related to clinical stage, and stage b was significantly higher than stage b, a, b and a (P <0.05). Conclusion: Serum CA12 5 level has certain value in the diagnosis of lung cancer. It is an important reference index for clinical staging, curative effect observation and prognosis judgment.