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目的观察MTX在异位妊娠腹腔镜保守手术前应用的疗效。方法将63例输卵管壶腹部妊娠的患者分为术前应用MTX组(观察组)和术前不应用MTX组(对照组),观察两组的术中出血量、手术时间、术后HCG值下降率。结果观察组较对照组术中出血量少(P<0.01),手术中处理患侧输卵管的时间短(P<0.01),术后HCG值两组均有明显下降,组间差距无统计学意义(P>0.05)。结论MTX在输卵管妊娠腹腔镜保守手术前应用具有明显杀胚作用,能显著减少术中出血量,缩短手术时间,提高手术成功率,值得推广。
Objective To observe the effect of MTX before laparoscopic conservative surgery of ectopic pregnancy. Methods 63 cases of tubal ampulla pregnancy were divided into preoperative MTX group (observation group) and preoperative MTX group (control group). The blood loss, operation time and postoperative HCG value of two groups were observed rate. Results The blood loss in the observation group was less than that in the control group (P <0.01), and the treatment time was shorter (P <0.01). The postoperative HCG values were significantly decreased in both groups, with no significant difference between groups (P> 0.05). Conclusion MTX in tubal pregnancy laparoscopic conservative surgery before the application of a significant role in killing embryo, can significantly reduce the amount of intraoperative bleeding, shorten the operation time and improve the success rate of surgery, it is worth promoting.