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百草枯可通过消化道、皮肤黏膜等多途径对人体产生危害。急性百草枯中毒临床表现为皮肤黏膜、肺、肝脏、肾脏等单一或全身多脏器损伤。患者早期可无症状或仅有轻微的局部刺激症状,经过数小时至数天的潜伏期后病情可突然加重。急性百草枯中毒目前缺乏特效的治疗办法,其较长的潜伏期是临床救治的重要“时间窗”。血液净化对急性百草枯中毒的疗效仍有争议,但早期、反复血液净化可能挽救部分患者。百草枯血浓度与中毒临床表现及预后密切相关,其血浓度越高,对人体危害性越大,病死率也越高。
Paraquat can harm the human body through many channels, such as the digestive tract, skin and mucous membranes. Acute paraquat poisoning clinical manifestations of skin mucosa, lung, liver, kidney and other single or multiple organ injury. Patients may be asymptomatic early or only minor symptoms of local irritation, after a few hours to several days after the incubation period may suddenly aggravate the disease. Acute paraquat poisoning is currently lack of special treatment, the longer incubation period is an important “time window ” for clinical treatment. The efficacy of blood purification on acute paraquat poisoning is still controversial, but early, repeated blood purification may save some patients. Paraquat blood concentration and clinical manifestations of poisoning and prognosis are closely related to the higher the blood concentration, the greater the danger to human body, the higher the case fatality rate.