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目的观察规律性血液透析和不规律性血液透析尿毒症患者心血管并发症的发生情况。方法将86例尿毒症患者随机分成规律性血液透析组(每周2.5~3次)45例和不规律性血液透析组(每周1~1.5次)41例。两组均使用重组人红细胞生成素皮下注射,口服叶酸、维生素B12及铁剂,蛋白质摄入量在1 g/(kg·d)以上,血液透析治疗半年。观察两组低血压、高血压、心力衰竭、心律失常、心绞痛(或心肌梗死)的发生情况,差异有统计学意义(P<0.05)。结果规律性血液透析组较不规律性血液透析组低血压、高血压、心力衰竭、心律失常、心绞痛(或心肌梗死)的发生明显减少。结论规律性血液透析比不规律性血液透析患者心血管并发症明显减少,临床疗效佳。
Objective To observe the incidence of cardiovascular complications in patients with regular hemodialysis and irregular hemodialysis uremia. Methods Totally 86 uremic patients were randomly divided into regular hemodialysis group (n = 45) and hemodialysis group (n = 41). Both groups were given subcutaneous injection of recombinant human erythropoietin, folic acid, vitamin B12 and iron, protein intake above 1 g / (kg · d), hemodialysis for six months. The incidence of hypotension, hypertension, heart failure, arrhythmia and angina pectoris (or myocardial infarction) in the two groups were observed. The difference was statistically significant (P <0.05). Results Compared with the irregular hemodialysis group, the incidences of hypotension, hypertension, heart failure, arrhythmia and angina pectoris (or myocardial infarction) in regular hemodialysis group were significantly decreased. Conclusion Regular hemodialysis patients with irregular hemodialysis patients with cardiovascular complications significantly reduced, good clinical efficacy.