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目的探讨肾炎四味胶囊联合氯沙坦治疗慢性肾脏病蛋白尿的疗效。方法选择60例慢性肾脏病患者,随机分为对照组和治疗组,两组均禁用肾毒性药物,对照组给予低盐、低脂、优质蛋白质饮食,口服氯沙坦;治疗组在对照组基础上给予口服肾炎四味胶囊。结果治疗2、4、6个月两组尿蛋白定量比较差异均有统计学意义(均P<0.05),两组治疗前后尿素氮、血肌酐比较差异无统计学差异(均P>0.05)。对照组总有效率63.3%,治疗组总有效率90.0%。结论肾炎四味胶囊联合氯沙坦治疗慢性肾脏病蛋白尿起效快、效果好,且价格低廉,值得临床应用。
Objective To investigate the therapeutic effect of Shenyao Siwei capsule combined with Losartan on proteinuria of chronic kidney disease. Methods Sixty patients with chronic kidney disease were randomly divided into control group and treatment group. Nephrotoxic drugs were forbidden in both groups. Low-salt, low-fat, high-quality protein diet and losartan were given to the control group. In the control group, Give oral nephritis four flavor capsules. Results There was significant difference in urinary protein in the two groups between the two groups (all P <0.05). There was no significant difference between the two groups before and after treatment (P> 0.05). The total effective rate was 63.3% in the control group, and the total effective rate in the treatment group was 90.0%. Conclusion Shen Yan Siwei capsule combined with losartan in the treatment of chronic kidney disease proteinuria rapid onset, good effect, and the price is low, worthy of clinical application.