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一、序言治疗性电生理学问世仅三年,但对药物难治性心律失常已取得良好疗效。本文旨在阐明用电极导管传递高能量直流电电击的生物物理效应;导管消蚀术的合理应用;对现有的导管消蚀术资料做一梗概。二、导管放电的生物电效应当电极导管传递200~400焦耳(J)电能时,在电极表面积聚2000~3000V电势。放电产生爆炸性闪光伴随有传递介质的温度和压力升高。强电场和高气压引起细胞膜的稳定性和结构损伤,电凝造成局部和远端组织损伤。放电引起心房、心室和房室结具有特征性的组织学改变,放电即刻在电极附近出现
First, the preface Therapeutic electrophysiology came out only three years, but the drug refractory arrhythmia has achieved good results. This article aims to elucidate the biophysical effects of high-energy DC shock delivered with lead electrodes, the rational use of catheter ablation, and an overview of existing catheter ablation data. Second, the biological effects of catheter discharge When the electrode catheter delivery of 200 ~ 400 J (J) power, the surface of the electrode to accumulate 2000 ~ 3000V potential. An explosive flash of discharge is accompanied by an increase in the temperature and pressure of the transfer medium. Strong electric field and high pressure cause cell membrane stability and structural damage, coagulation caused by local and remote tissue damage. Discharges cause a characteristic histological change in the atria, ventricles, and atrioventricular nodes that appear immediately near the electrodes