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目的苯接触时间越久就越容易造成慢性苯中毒,骨髓是苯慢性中毒的主要靶器官,引起各种血液类疾病,因此调查分析职业性慢性苯中毒临床情况有利于预防职业苯中毒。方法选择2005-2015年吉林市职业病防治院诊治的职业性慢性苯中毒112例,查阅病历资料,调查患者临床表现,治疗与转归等项目。结果职业性慢性苯中毒112例中轻度苯中毒38例,中度职业性慢性苯中毒68例,重度职业性慢性苯中毒6例。38例轻度中毒白细胞数目仍<4×109/L,无恢复;68例中度中毒中有24例患者白细胞数目在(3~4)×109/L之间。结论苯中毒防治仍是不可忽视的问题。应加强职业病防治监督、管理工作,对工人进行上岗前、在岗期间、离岗时的健康检查,有效控制职业病和职业中毒事件的发生。
Objective The longer the contact time of benzene, the more likely to cause chronic benzene poisoning, bone marrow is the main target organ of chronic benzene poisoning, causing a variety of blood diseases, so the investigation and analysis of clinical conditions of occupational chronic benzene poisoning is conducive to the prevention of occupational benzene poisoning. Methods Select 112 cases of occupational chronic benzene poisoning diagnosed and treated in Jilin City Occupational Disease Prevention and Treatment Hospital from 2005 to 2015, review the medical records, investigate the clinical manifestations, treatment and outcome of the patients. Results Occupational chronic benzene poisoning in 112 cases of mild benzene poisoning in 38 cases, 68 cases of moderate occupational chronic benzene poisoning, severe occupational chronic benzene poisoning in 6 cases. 38 cases of mild poisoning leukocytes still <4 × 109 / L, no recovery; 68 cases of moderate poisoning in 24 patients with leukocytes in (3 ~ 4) × 109 / L between. Conclusion Benzene poisoning prevention and treatment is still not negligible problem. The prevention and control of occupational diseases should be strengthened and management should be strengthened. Health checkup before, during and after leaving the posts for workers should be strengthened to effectively control the occurrence of occupational diseases and occupational poisonings.