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局部用的抗真菌药物主要分3类,即:聚烯类、咪唑类和消毒剂,然治疗失败的较多,故开始寻找新的抗真菌药物。1987年12 月从儿科肝移植患者胆汁中培养的白念珠菌敏感试验发现对各种抗真菌药物耐药的菌株用Mupirocin非常敏感。继之,局部用2%的Mupirocin治疗对多种抗真菌药耐药的烧伤葡萄球菌感染与体外试验调查发现,Mupirocin对白念珠菌、金黄色葡萄球菌感染的伤口有杀真菌作用。2%Mupirocin对白念珠菌的抑菌圈与其他常用的6种局部抗真药物可比美,故是一种新的局部
Topical antifungal drugs are mainly divided into three categories, namely: polyenes, imidazoles and disinfectants, but failed to treat more, it began looking for new antifungal drugs. The C. albicans susceptibility test in bile from pediatric liver transplant patients in December 1987 found that strains resistant to various antifungal agents were very sensitive to Mupirocin. In the second place, Mupirocin, a fungicide-resistant Burn Staphylococcus aureus (MRSA) in vitro and in vitro, was investigated with 2% Mupirocin and found to have fungicidal effects on C. albicans and S. aureus-infected wounds. 2% Mupirocin Candida albicans inhibition zone and other commonly used 6 kinds of local anti-true drugs comparable to the United States, it is a new part