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目的观察铝碳酸镁联合莫沙必利对胆汁反流性胃炎的临床疗效。方法选择经证实为胆汁反流性胃炎80例患者,分为治疗组42例,对照组38例。其中治疗组予以用莫沙必利和铝碳酸镁,治疗4周后比较观察两组患者在临床疗效,上腹痛、饱胀感等症状变化及胃镜下改变的变化。结果治疗组与对照组比较总有效率、临床症状及胃镜下改善明显,两组比较差异有显著性(P<0.01)。结论铝碳酸镁联合莫沙必利联合应用可有效缓解胆汁反流性胃炎症状,是治疗胆汁反流性胃炎的有效药物。
Objective To observe the clinical efficacy of aluminum magnesium carbonate combined with mosapride on bile reflux gastritis. Methods Eighty patients with proven bile reflux gastritis were selected and divided into treatment group (n = 42) and control group (n = 38). The treatment group was treated with mosapride and magnesium aluminum carbonate. After 4 weeks of treatment, the changes of clinical symptoms, upper abdominal pain, fullness and other symptoms and changes under endoscopy were observed. Results Compared with the control group, the total effective rate, clinical symptoms and endoscopic findings were significantly improved in the treatment group and the control group, with significant difference between the two groups (P <0.01). Conclusion Combined application of aluminum magnesium carbonate and mosapride can effectively relieve the symptoms of bile reflux gastritis and is an effective drug for the treatment of bile reflux gastritis.