Regenerative medicine by cell transplantation is a novel therapy for treating end-stage organ failure and tissue damage.Cell-based therapy based on the transplantation of neural stem/progenitor cells(NSPCs)represents an attractive strategy for the treatment of neurodegenerative diseases,but obtaining large numbers of these cells is difficult and their differentiation potential is strictly restricted in a spatiotemporally-regulated manner during central nervous Regenerative medicine by cell transplantation is a novel therapy for treating end-stage organ failure and tissue damage. Cell-based therapy based on the transplantation of neural stem / progenitor cells (NSPCs) represents an attractive strategy for the treatment of neurodegenerative diseases. large numbers of these cells is difficult and their differentiation potential is strictly restricted in a spatiotemporally-regulated manner during central nervous