目的　探讨一种新式改良Indiana新膀胱术的适应证、手术方法并对疗效进行评估。方法　对 5例膀胱癌患者施行全膀胱切除术加改良Indiana新膀胱术。结果　 5例患者均获得满意的疗效 ,自行导尿顺利。随访 6～ 30个月 ,均尿控满意 ,排尿次数 5～ 6次 /昼 ,1～ 3次 /夜。其中 4例行造影 ,新膀胱呈球形 ,容量 40 0～ 5 0 0毫升 ,无输尿管尿液返流。结论　改良Indiana膀胱术具有操作容易 ,贮尿囊低压容量大 ,抗返流机制可靠 ,尿控满意 ,并发症少的优点 ,值得在临床推广。 Objective To explore a new type of indications and surgical methods to improve Indiana neobladder surgery and evaluate its curative effect. Methods Five patients with bladder cancer underwent total cystectomy plus modified Indiana neobladder. Results 5 patients were satisfied with the efficacy of self-catheterization smoothly. Follow-up 6 to 30 months, are satisfied with the urine control, urination frequency 5 ~ 6 times / day, 1 ~ 3 times / night. 4 cases of angiography, the new bladder was spherical, the capacity 40 0 ​​~ 500 ml, no ureteral reflux. Conclusion Improved Indiana Bladder Surgery has the advantages of easy operation, low storage capacity, reliable anti-reflux mechanism, satisfactory urine control and fewer complications. It is worthy of clinical promotion.