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为了了解成年大鼠运动皮层（ＭＩ）的功能可塑性，利用皮层内微刺激方法测定ＭＩ代表区并观察重复电刺激前肢神经对ＭＩ代表区的影响。实验组大鼠（９例）持续１．５～２小时的前肢神经电刺激导致前肢运动区（ＦＬ）与面部触须运动区（ＶＩ）边界向ＶＩ方向移动２６３．３±９０．９μｍ（Ｍ±ＳＤ）并同时伴有运动阈值（ＭＴ）的改变：ＦＬ内ＭＴ降低５．０±１３．３μＡ，而在ＶＩ内ＭＴ升高９．６±１１．６μＡ（Ｐ均＜０．０１）。对照组大鼠（６例）间隔１．５～２小时的两次测定结果，ＦＬ－ＶＩ边界移动为２９．７±４３．２μｍ，ＭＴ无明显改变。这一结果表明体表转入输入的改变可快速地引起ＭＩ神经元输出特性的改变。
In order to understand the functional plasticity of motor cortex (MI) in adult rats, the cortical microdosing method was used to determine the area of MI and to observe the effect of repeated electrical stimulation of the forelimb nerve on the area of MI. Rats in the experimental group (n = 9) had neurological stimulation of the forelimb for 1.5 to 2 hours leading to a VI shift of 263.3 ± 90.9 μm (M ± y) in the forelimb movement area (FL) and facial tentorium movement area (VI) SD), accompanied by a change in motor threshold (MT): 5.0 ± 13.3μA for MT in FL and 9.6 ± 11.6μΑ for VI in VI (all P <0.01). The control group rats (6 cases) interval of 1.5 to 2 hours of the two measurements, FL-VI border movement of 29.7 ± 43.2μm, MT no significant change. This result indicates that changes in the importation of the surface of the body rapidly cause changes in the output characteristics of MI neurons.