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目的:探讨静脉窦血栓形成(CVST)的病因、临床表现、影像学改变、治疗及预后。方法:分析45例CVST患者的临床表现、影像学特征、脑脊液检查、治疗及预后。结果:45例头颅CT检查21例有阳性发现。MRI 39例28例有异常改变。MRV 20例均见相应静脉窦显影缺失。3例DSA检查均有阳性发现。采用脱水、抗凝、抗血小板、激素等治疗。治愈32例,好转11例,死亡2例。结论:对临床以颅内压增高为主要表现,伴或不伴局灶表现者,应考虑CVST,早期抗凝治疗为首选。
Objective: To investigate the etiology, clinical manifestations, imaging changes, treatment and prognosis of sinus thrombosis (CVST). Methods: The clinical manifestations, imaging features, cerebrospinal fluid examination, treatment and prognosis of 45 patients with CVST were analyzed. Results: 45 cases of skull CT examination of 21 cases were positive. MRI 39 cases of 28 patients with abnormal changes. MRV 20 cases were seen corresponding sinus development missing. Three cases of DSA were found positive. Using dehydration, anticoagulant, anti-platelet, hormones and other treatment. 32 cases were cured, 11 cases improved and 2 died. Conclusion: The clinical manifestations of increased intracranial pressure, with or without focal manifestations, should consider CVST, early anticoagulant therapy is preferred.