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目的：探讨茶多酚治疗肾炎的机理。方法：小鼠灌胃茶多酚７ 天后测其免疫功能和抗氧化酶的活性。结果：茶多酚可明显抑制小鼠腹腔巨噬细胞及其因子ＩＬ１ 的活性和ＮＯ 的生成；抑制小鼠脾细胞产生抗体的能力和血清ＣＩＣ 的含量；抑制小鼠脾细胞增殖反应和总Ｔ 细胞花环和ＴＨ 花环的形成。茶多酚还可增强小鼠红细胞ＳＯＤ 和血中ＧＳＨＰＸ 的活性，抑制血清中ＬＰＯ 的生成。结论：茶多酚抑制小鼠免疫功能、增强小鼠抗氧化酶的活性可能是其治疗肾炎的机理之一
Objective: To investigate the mechanism of tea polyphenols in the treatment of nephritis. Methods: Mice were intragastrically administered with polyphenols for 7 days to measure their immune function and antioxidant enzyme activity. Results: Tea polyphenols can significantly inhibit peritoneal macrophages and their factors IL 1 activity and NO generation; inhibition of mouse spleen cells to produce antibodies and serum CIC content; inhibit mouse spleen cell proliferation response and Total T cell rosette and TH rosette formation. Tea polyphenols can also increase the mouse erythrocyte superoxide dismutase and blood GSH PX activity, inhibit the production of LPO in serum. Conclusion: Tea polyphenols can inhibit the immune function of mice and enhance the activity of anti-oxidase in mice may be one of the mechanisms of treatment of nephritis