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目的 探讨SARS患者外周血T淋巴细胞亚群的变化。方法 用流式细胞仪检测44例SARS住院患者外周血T淋巴细胞亚群,并测定其白细胞计数及分类。结果 与正常组比较,SARS组白细胞总数显著下降,淋巴细胞百分数和绝对数显著下降,粒细胞绝对数显著下降,粒细胞百分数显著增加;CD3~+、CD4~+、CD8~+细胞百分数,CD4~+/CD8~+比值差异无统计学意义。结论 SARS患者外周血淋巴细胞减少,T淋巴细胞亚群无明显变化。
Objective To investigate the changes of T lymphocyte subsets in peripheral blood of SARS patients. Methods Flow cytometry was used to detect T lymphocyte subsets in peripheral blood of 44 SARS patients and their white blood cell count and classification were determined. Results Compared with the normal control group, the total number of white blood cells in SARS group decreased significantly, the percentage of lymphocytes and absolute number decreased significantly, the absolute number of granulocytes decreased significantly and the percentage of granulocytes increased significantly. The percentage of CD3 +, CD4 +, CD8 + ~ + / CD8 ~ + ratio was no significant difference. Conclusion The peripheral blood lymphocytes and the T lymphocyte subsets of SARS patients have no obvious changes.