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目的:评价加替沙星与左氧氟沙星用于治疗泌尿系感染患者的成本-效果。方法:选取2014年1月—2015年2月收治的泌尿系感染患者116例,将其分为A组58例和B组58例;A患者均给予加替沙星葡萄糖注射液治疗;B组患者均给予乳酸左氧氟沙星氯化钠注射液治疗,比较两组患者治疗后的总有效率、细菌清除率和治疗后的疗效-成本。结果:经加替沙星葡萄糖注射液治疗后的A组患者的总有效率为94.83%,高于经乳酸左氧氟沙星氯化钠注射液的B组患者为89.66%(P>0.05);前者的不良反应发生率为8.62%,后者为10.34%(P<0.05);A组患者的治疗成本-效果比值为816.16/94.83=8.61;B组患者的治疗成本-效果比值为618.29/89.66=6.90。结论:采用乳酸左氧氟沙星氯化钠注射液治疗泌尿系感染患者的治疗成本-效果优于加替沙星葡萄糖注射液。
OBJECTIVE: To evaluate the cost-effectiveness of gatifloxacin and levofloxacin in the treatment of patients with urinary tract infections. Methods: A total of 116 patients with urinary tract infection were enrolled from January 2014 to February 2015. They were divided into group A (58 cases) and group B (58 cases). Patients in group A received gatifloxacin glucose injection. Group B All patients were treated with levofloxacin lactate sodium injection. The total effective rate, bacterial clearance rate and therapeutic effect - cost after treatment were compared between the two groups. Results: The total effective rate of group A treated with gatifloxacin and glucose injection was 94.83%, which was 89.66% (P> 0.05) higher than that of group B treated with levofloxacin and sodium chloride injection. The former was poor The response rate was 8.62% and the latter was 10.34% (P <0.05). The treatment cost-effectiveness ratio was 816.16 / 94.83 = 8.61 in group A and 618.29 / 89.66 = 6.90 in group B. CONCLUSIONS: The cost of treatment with urinary tract infection with levofloxacin lactate injection is superior to gatifloxacin glucose injection.