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目的:研究探讨米非司酮配伍甲氨蝶呤对宫外孕的临床治疗效果。方法:选取我院2012年5月~2014年6月收治的100例宫外孕患者,经本院伦理委员会批准、患者本人知情同意下,分对照组患者50例,单独采用米非司酮治疗,研究组患者50例,采用米非司酮配伍甲氨蝶呤治疗,随访观察两周,对比两组患者临床治疗效果。结果:对照组患者包块缩小、腹痛消失等临床指标改善人数比率与研究组患者包块缩小、腹痛消失等临床指标改善人数比率,组间对比差异具有统计学意义(P<0.05)。结论:米非司酮配伍甲氨蝶呤治疗宫外孕疗效确切,具有一定临床推广使用价值。
Objective: To study the clinical effect of mifepristone combined with methotrexate on ectopic pregnancy. Methods: 100 cases of ectopic pregnancy admitted to our hospital from May 2012 to June 2014 were selected and approved by our hospital ethics committee. Fifty patients in the control group were treated with mifepristone alone with the informed consent of the patients. Group of 50 patients, the use of mifepristone methotrexate treatment, followed up for two weeks, compared the clinical efficacy of two groups of patients. Results: In the control group, the ratio of improvement of clinical indexes such as shrinkage of the mass and disappearance of abdominal pain and the improvement rate of clinical indexes such as the shrinkage of the mass and disappearance of abdominal pain in the study group were statistically significant (P <0.05). Conclusion: Mifepristone with methotrexate treatment of ectopic pregnancy exact effect, with a certain clinical value of the promotion.