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目的探讨阿奇霉素治疗呼吸道感染的临床疗效。方法选取2014年2~6月医院呼吸内科确诊的呼吸道感染患者70例,随机分为治疗组与对照组各35例,治疗组予阿奇霉素治疗;对照组予头孢唑林钠治疗。观察2组临床治疗效果及不良反应发生情况。结果治疗组总有效率94.29%明显高于对照组的74.29%,差异有统计学意义(P<0.05)。治疗组发生不良反应2例(5.71%);对照组发生不良反应4例(11.43%),治疗组低于对照组(P<0.05)。结论阿奇霉素治疗呼吸道感染,具有半衰期长、组织浓度高、用药量小、疗程短、临床疗效好、药物不良反应少等优点,值得临床推广应用。
Objective To investigate the clinical efficacy of azithromycin in the treatment of respiratory tract infections. Methods Seventy patients with respiratory tract infection diagnosed in Department of Respiratory Medicine from February to June 2014 were randomly divided into treatment group and control group with 35 cases each. The treatment group was treated with azithromycin and the control group was treated with cefazolin sodium. The clinical effects and adverse reactions in 2 groups were observed. Results The total effective rate was 94.29% in the treatment group was significantly higher than 74.29% in the control group, the difference was statistically significant (P <0.05). There were 2 adverse reactions (5.71%) in the treatment group and 4 (11.43%) adverse reactions in the control group. The treatment group was lower than the control group (P <0.05). Conclusion Azithromycin has the advantages of long half-life, high tissue concentration, small dosage, short course of treatment, good clinical curative effect and few adverse drug reactions. It is worthy of clinical application.