患者武某,女,51a。因尿频尿急尿痛,口服诺氟沙星胶囊0.2g,共2次,次日全身发痒。因过去有磺胺、青霉素等药物过敏史,故停服诺氟沙星,用抗过敏药治疗2d,痒减轻。患者于d3又服用诺氟沙星0.2g,当晚搔痒加剧,用地塞米松静滴3d,无效,数月后出现巩膜及皮肤黄染,因剧痒失眠疲乏。查体:皮肤向心性黄染, Patient Wu, female, 51a. Urinary urgency due to urinary pain, oral norfloxacin capsules 0.2g, a total of 2 times the next day the whole body itching. In the past because of sulfa, penicillin and other drug allergy history, so stop taking norfloxacin, with anti-allergy treatment 2d, itching to reduce. Patients d3 and taking norfloxacin 0.2g, itchy aggrandizement that night, intravenous infusion of dexamethasone 3d, invalid, a few months after the sclera and skin yellow dye, due to drama itch insomnia tired. Physical examination: the skin concentric yellow dye,