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作者在菲律宾马尼拉San Lazaro医院,对疟疾与葡萄糖-6-磷酸脱氢酶(G-6-PD)缺乏的关系,及抗氯喹恶性疟进行了初步研究。68例患者全部住院,男性42例,女性26例,年龄11～30岁。36例恶性疟,28例问日疟,两者混合感染4例。主要临床表现为发热、面色苍白、寒战、头痛、腹痛、出汗和关节肌肉酸痛;主要体征为肝、脾肿大与黄疸。部分症状体征不典型。其中57%的病人入院时即诊断为疟疾,其余则被误诊,后由血涂片确诊。对病人作了血、尿、粪常规及血液化学检查。后者包括SGPT、SGOT、乳酸脱氢酶、碱性磷酸酶、总胆红质、血尿素氮及G-6-PD。每
The authors conducted a preliminary study of the relationship between malaria and the absence of glucose-6-phosphate dehydrogenase (G-6-PD) and chloroquine-resistant P. falciparum at San Lazaro Hospital, Manila, Philippines. 68 patients were hospitalized, 42 males and 26 females, aged 11 to 30 years. 36 cases of falciparum malaria, 28 cases of vivax malaria, the two mixed infection in 4 cases. The main clinical manifestations are fever, pale, chills, headache, abdominal pain, sweating and joint soreness; the main signs of liver, splenomegaly and jaundice. Some symptoms and signs are not typical. 57% of them were diagnosed with malaria on admission and the rest were misdiagnosed and confirmed by blood smears. The patient made blood, urine, fecal routine and blood chemical tests. The latter includes SGPT, SGOT, lactate dehydrogenase, alkaline phosphatase, total bilirubin, blood urea nitrogen and G-6-PD. each