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我们于1991年1月～1992年12月,应用前列腺素E_1和清栓酶(蝮蛇抗栓酶)治疗肺心病并冠心病(以下简称双心病)性心力衰竭20例,疗效显著,现报道如下。 1 临床资料 1.1 病例选择 按照1977年全国肺心病会议诊断标准和1985年实用内科杂志第12期白素华等制定的肺心病合并冠心病的诊断标准,将入院病人随机分为治疗及对照组各20例。治疗组:男14例,女6例,年龄46～70岁,平均62岁。对照组:男12例,女8例,年龄43～68岁,平均60岁。两组病程均在6～32年,入院时均有肺部感染、心力衰竭的症状和体征。治疗组Ⅳ级心功能15例,Ⅲ级心功能5例:对照组Ⅳ级心功能14例,Ⅲ级心功能6例(按NYHA分级标准)。并分别伴有左室肥厚劳损、心肌缺血、房颤
We in January 1991 ~ December 1992, the application of prostaglandin E_1 and Qing bolt enzyme (viper antithrombin enzyme) treatment of pulmonary heart disease and coronary heart disease (hereinafter referred to as double heart disease) 20 cases of heart failure, the effect is significant, it is reported as follows. 1 Clinical data 1.1 Case Selection In accordance with the diagnostic criteria of the National Conference on Cor Pulmonary Disease in 1977 and the diagnostic criteria of Coronary heart disease complicated with cor pulmonale established by Baihuahua et al., No. 12, The Practical Internal Medicine, 1985, the admitted patients were randomly divided into treatment and control groups of 20 cases . Treatment group: 14 males and 6 females, aged 46 to 70 years, mean 62 years. Control group: 12 males and 8 females, aged 43 to 68 years, mean 60 years. Course of disease in both groups in 6 to 32 years, admitted to the hospital have pulmonary infection, heart failure symptoms and signs. Treatment group Ⅳ grade cardiac function in 15 cases, Ⅲ grade heart function in 5 cases: control group Ⅳ grade 14 cases of cardiac function, Ⅲ grade cardiac function in 6 cases (according to NYHA classification criteria). And were associated with left ventricular hypertrophy strain, myocardial ischemia, atrial fibrillation