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本文叙述急性病毒性心肌炎的不同治疗方法,重点是实验室研究及卡托普利可能的作用。 抗炎药:非甾体类抗炎药曾经验性地应用于急性病毒性心肌炎的治疗(尤其是合并心包炎者)。然而,在感染柯萨奇病毒B3小鼠模型研究中,发现疾病早期使用吲哚美辛(Inaomethacin)、水扬酸钠、布洛芬(ibupro-fen)会加重病情,后期应用未加重病变,但也无有益作用。故该病急性期应避免使用非甾体类抗炎药,慢性期应限制这种安慰性的治疗。
This article describes different treatments for acute viral myocarditis, with a focus on laboratory studies and the possible role of captopril. Anti-inflammatory drugs: Non-steroidal anti-inflammatory drugs have been used empirically in the treatment of acute viral myocarditis (especially with pericarditis). However, in the study of coxsackievirus B3 mouse model, it was found that in the early stage of the disease, Inaomethacin, sodium salicylate and ibupro-fen increased the severity of the disease, But no useful effect. Therefore, the acute phase of the disease should avoid the use of non-steroidal anti-inflammatory drugs, chronic phase should limit such soothing treatment.