论文部分内容阅读
目的评价超声引导下16G空芯针穿刺活检对乳腺病灶诊断的准确性。方法在这项回顾性研究中,我们对693例女性患者的732个病灶进行超声引导下16G空芯针穿刺活检及随后的开放性手术。开放性手术的病理结果作为最终结果(金标准)。分别评估总体和三个亚组(≤1cm、≤2cm、>2cm)的符合率、高危低估率、导管原位癌低估率、漏诊率、敏感性、特异性和假阴性率。结果 732个乳腺病灶的穿刺活检病理结果中恶性占66%,高危病灶占4%,良性占30%。总体穿刺的符合率为97.1%(711/732),低估率2.7%(20/732),假阴性率0.2%(1/493)。三个亚组(≤1cm组、≤2cm组、>2cm组)的符合率、低估率、漏诊率、敏感性、特异性和假阴性率均无显著差异(P>0.05)。结论对于评估乳腺病灶,超声引导下16G空芯针穿刺活检是一种准确的技术方法。对于穿刺活检病理为高危的病例,因存在相对较高的低估率,开放性手术是必要的。
Objective To evaluate the diagnostic accuracy of 16G needle guided biopsy for breast lesions under ultrasound guidance. Methods In this retrospective study, we performed 16G needle-aspiration biopsy and subsequent open surgery on 732 lesions in 693 women. Pathology results of open surgery as the final result (gold standard). The coincidence rates, the high-risk underestimation rates, the underestimation rates of ductal carcinoma in situ, the misdiagnosis rates, the sensitivity, the specificity and the false-negative rates of the total and three subgroups (≤1cm, ≤2cm,> 2cm) were evaluated respectively. Results The results of biopsy of 732 breast lesions were 66% malignant, 4% high risk and 30% benign. The overall compliance rate was 97.1% (711/732), the underestimation rate was 2.7% (20/732), and the false negative rate was 0.2% (1/493). The coincidence rate, underestimation rate, misdiagnosis rate, sensitivity, specificity and false negative rate of the three subgroups (≤1cm group, ≤2cm group,> 2cm group) had no significant difference (P> 0.05). Conclusion For the assessment of breast lesions, ultrasound-guided 16G needle core needle biopsy is an accurate technique. For the high-risk biopsy biopsy cases, due to the existence of a relatively high rate of underestimation, open surgery is necessary.