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本文报道检测260例肾小球疾病患儿血清中HBsAg,结果35例<+>,占13.5%。其中伴有抗-HBc及HBeAg(+)者12例,单纯伴有抗-HBc(+)11例,伴HBeAg(+)5例,故具备二项及三项HBV相关抗原(+)者共28例,占80%。此35例中,过去有肝炎史者5例,肝功能检查34例中11例异常,占32%。部分病例同时检测血清补体C_3、CH_(50)及循环免疫复合物CIC。结合病史,符合乙型肝炎相关性肾炎诊断者共31例,占检测总数260例的11.9%。本文最后提出四项乙型肝炎相关性肾炎临床诊断标准。
This paper reports the detection of 260 cases of glomerular disease in children with HBsAg, the results of 35 cases <+>, accounting for 13.5%. There were 12 cases with anti-HBc and HBeAg (+), 11 cases with anti-HBc (+) alone and 5 cases with HBeAg (+), so they had two or three HBV-related antigens 28 cases, accounting for 80%. Among the 35 cases, there were 5 cases of past history of hepatitis and 11 cases of abnormal liver function test, accounting for 32%. In some cases, serum complement C_3, CH_ (50) and circulating immune complex CIC were detected simultaneously. Combined with the history, in line with the diagnosis of hepatitis B-related nephritis in a total of 31 cases, accounting for a total of 11.9% of the total number of tests. Finally, this paper proposes four clinical diagnostic criteria for hepatitis B-related nephritis.