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目的:本研究旨在研究口服蜂巢提取物改善过敏性鼻炎患者生活质量情况。方法:采用口服大、小不同剂量蜂巢提取物治疗过敏性鼻炎,1周为1个疗程,共服用4个疗程。观察两组患者治疗4个疗程与停药随访1个月的生活质量改善情况。主要观察在眼部、鼻部症状、非鼻眼症状、情感症状等方面的变化。结果:两组患者治疗前生活质量明显较低。口服大剂量与小剂量蜂巢提取物均能显著改善过敏性鼻炎患者的各项生活质量指标,而两组效果差异无明显统计学意义。停服30 d后疗效仍然显著,但小剂量组患者在实际问题、鼻部症状、非鼻眼症状等方面的改善有呈复发趋势,大剂量组相对改善较平稳。故此蜂巢剂可有效改善过敏性鼻炎患者临床症状及生活质量,且蜂巢来源广泛,天然安全,用法简单,口感甘甜,疗效确切,值得临床研究开发及推广应用,以造福反复受过敏性鼻炎困扰的广大患者。
Objectives: This study was designed to investigate the effect of oral hive extract on improving quality of life in patients with allergic rhinitis. Methods: Oral large and small different doses of honeycomb extract for the treatment of allergic rhinitis, 1 week for a course of treatment, taking a total of 4 courses. The quality of life of the two groups was observed after 4 courses of treatment and one month after the withdrawal. The main observation in the eye, nasal symptoms, non-nasal symptoms, emotional symptoms and other changes. Results: The quality of life of the two groups before treatment was significantly lower. Oral high-dose and low-dose honeycomb extract can significantly improve the quality of life of patients with allergic rhinitis index, but no significant difference between the two groups was statistically significant. After 30 days of treatment, the curative effect was still significant, but there was a recurrence trend in the practical problems, nasal symptoms and non-nasal symptoms in the low-dose group, and the relative improvement in the high-dose group was relatively stable. Therefore, the honeycomb agent can effectively improve the clinical symptoms and quality of life of patients with allergic rhinitis, and the honeycomb has a wide range of sources, natural safety, simple usage, sweet taste and curative effect, which is worthy of clinical research and development and popularization and application for the benefit of repeatedly suffering from allergic rhinitis The majority of patients.