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目的:探讨705例良性前列腺增生(BPH)患者下尿路症状(LUTS)特点及危险因素.方法:对2012年10月至2016年10月共705例在我院住院治疗的BPH的患者进行回顾分析,采用了国际前列腺症状评分问卷(IPSS)对BPH相关的LUTS进行评估,进一步分析其特点和危险因素.结果:705例患者中轻度、中度和重度LUTS的比例分别为43(6.1％)、477(67.7％)和185(26.2％).随着年龄的增加、tPSA的升高、前列腺体积的增大,患者IPSS评分显著增加(均有P＜0.05).单因素和多因素Logistics分析发现年龄(OR:1.048,95％CI:1.011～1.087)和前列腺体积(OR:1.024,95％CI:1.006～1.043)是中重度LUTS的独立危险因素.结论:年龄增长和前列腺体积增大是促进BPH患者中重度LUTS发生的独立危险因素,临床中对于前列腺体积增大的老年BPH患者应予以积极的治疗,防止LUTS的加重.","Objective To investigate the characteristic and risk factors of lower urinary tract symptoms (LUTS) in patients with benign prostate hyperplasia (BPH).Methods A total of 705 BPH patients from October 2012 to October 2016 were retrospective analysis. The inteational prostate symptom score (IPSS) questionnaire was used for the evaluation of LUTS in BPH patients and we further analyzed its characteristics and risk factors.Results In the 705 patients, the proportion of mild, moderate and severe LUTS were 43 (6.1％), 477 (67.7％) and 185(26.2％). With the increase of age, tPSA and prostate volume, the IPSS increased significantly (P＜0.05). Univariate and multivariate logistics analysis found that age (OR:1.048,95％CI:1.011-1.087) and prostate volume (OR:1.024, 95％CI: 1.006-1.043) were independent risk factors for moderate and severe LUTS. Conclusions The increase of age and prostate volume will increase the incidence of moderate and severe LUTS. When faced with elderly BPH patients with increasement of prostate volume, treatment should be taken positively to prevent the progression of LUTS.