高级氧化蛋白产物(AOPP)是在氧化应激过程中对机体产生的一系列病理生理性作用的一组蛋白质产物的总称,而其所介导的氧化应激作用是糖尿病相关性牙周炎加重的发病机制之一。本文就AOPP的结构及其理化特性,AOPP的合成和分离及鉴定,AOPP与糖尿病相关性牙周炎的关系,糖尿病相关性牙周炎的治疗等研究进展作一综述。 Advanced Oxidation Protein Products (AOPP) is a collective term for a group of protein products that exert a series of pathophysiological effects on the body during oxidative stress and its mediated oxidative stress is aggravating in diabetic-associated periodontitis One of the pathogenesis. This review summarizes the research progress on the structure and physicochemical properties of AOPP, the synthesis and isolation of AOPP, the relationship between AOPP and diabetic periodontitis, and the treatment of diabetic associated periodontitis.