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目的研究氟哌噻吨美利曲辛对于并发有抑郁症的胃溃疡患者的临床治疗效果。方法研究选取2012年12月至2013年12月我院消化内科患有胃溃疡伴有抑郁症的患者32例。将32例患者采用随机分组的方法,平均分为两组,分别为氟哌噻吨美利曲辛组和对照组。对照组患者给予常规的胃溃疡药物治疗。氟哌噻吨美利曲辛组患者在对照组患者的药物治疗方案的基础上给油氟哌噻吨美利曲辛。观察两组患者在治疗后的胃溃疡治疗情况以及汉密顿抑郁量表评分情况。结果氟哌噻吨美利曲辛组患者的胃溃疡总有效率为87%,对照组患者的胃溃疡总有效率为57%。氟哌噻吨美利曲辛组治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。氟哌噻吨美利曲辛组治疗后汉密顿抑郁量表评分下降程度明显大于对照组,差异具有统计学意义(P<0.05)。结论氟哌噻吨美利曲辛不仅可以治疗胃溃疡,还能降低患者的抑郁量表评分,减轻患者抑郁症状。
Objective To study the clinical efficacy of flupentixol and melitracen in patients with gastric ulcer complicated by depression. Methods From December 2012 to December 2013, 32 patients with gastric ulcer and depression were admitted to our department of Gastroenterology. Thirty-two patients were randomly divided into two groups: flupentixol and melitracen, and control group. Patients in the control group were given conventional gastric ulcer medication. Flupenthixol-T and Melitracen-based patients were given flupentixol and melitracen on the basis of the drug treatment regimen of patients in the control group. Observe the treatment of gastric ulcer in both groups after treatment and the score of the Hamilton Depression Scale. Results The total effective rate of gastric ulcer was 87% in the flupentixol and melitracen group, while the total effective rate of gastric ulcer in the control group was 57%. The total effective rate of flupentixol and melitracen group was higher than that of control group, the difference was statistically significant (P <0.05). The decline of the Hamilton Depression Scale after flupentixol and melitracen treatment was significantly greater than that of the control group, with significant difference (P <0.05). Conclusions Flupentixol and melitracen can not only treat gastric ulcer, but also reduce the depression scale of patients and relieve the depressive symptom of patients.