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本文利用单片纸蝶法测定了14个苯基脲类化合物抑制金黄葡萄球菌和大肠杆菌的抑制活性;采用量子化学计算方法中的PM3软件进行了量化计算,计算结果与活性测试结果基本相吻合。
In this paper, the determination of the inhibitory activity of 14 phenylureas against Staphylococcus aureus and Escherichia coli was determined by the monolithic paper-butterfly method. Quantitative calculations were carried out using the PM3 software in quantum chemical calculation method. The calculated results are in good agreement with the results of the activity test .