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目的:探讨分析在第二产程末肛塞米索前列醇加催产素静滴预防产后出血的疗效。方法:将我院妇产科收治的82名健康足月且正常经阴道分娩的产妇随机分为治疗组和对照组。治疗组产妇在第二产程末使用肛塞米索前列醇加催产素静滴,对照组仅采用静滴催产素进行治疗。观察并记录两组产妇第三产程所用的时间以及产后2小时以及24小时内的阴道出血量。对比分析两组产妇产后出血的发生率,以及血压、心率的变化。结果:治疗组第三产程时间明显低于对照组,且产后出血量均低于对照组。治疗组发生产后出血的几率低于对照组,两组比较有统计学差异(P<0.05)。结论:第二产程末使用肛塞米索前列醇加催产素静滴可起到协同互补的作用,可有效预防产后出血,降低产妇死亡率,值得在临床推广应用。
Objective: To investigate the effect of analgesic misoprostol plus oxytocin intravenous infusion on the prevention of postpartum hemorrhage at the end of the second stage of labor. Methods: 82 maternal obstetrics and gynecology admitted to our hospital healthy and normal vaginal delivery of women were randomly divided into treatment group and control group. In the treatment group, the analgesic misoprostol plus oxytocin intravenous infusion was used at the end of the second stage of labor, while the control group was treated with intravenous oxytocin only. Observe and record the two groups of women during the third stage of labor and the amount of vaginal bleeding within 2 hours and 24 hours after delivery. The incidence of postpartum hemorrhage, blood pressure and heart rate in two groups were compared and analyzed. Results: The treatment group, the third stage of labor was significantly lower than the control group, and postpartum hemorrhage were lower than the control group. The incidence of postpartum hemorrhage in the treatment group was lower than that in the control group, with statistical significance (P <0.05). Conclusion: The second stage of labor using anal suppository plus intravenous infusion of oxytocin can play a synergistic complementary role, which can effectively prevent postpartum hemorrhage and reduce maternal mortality, it is worth in the clinical application.