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[目的]了解泰安市2011年各种疫苗预防接种异常反应的发生情况,评价泰安市疑似预防接种异常反应(AEFI)监测系统的运行状况。[方法]对泰安市2011年疑似预防接种异常反应病例进行描述性流行病学分析。[结果]2011年泰安市共有25种疫苗引起AEFI,共276例,报告发生率为15.66/10万。276例中,一般反应占94.93%,异常反应占4.35%,偶合症占0.72%;男性占57.97%,女性占42.03%;<1岁儿童占62.32%。发生AEFI最多的疫苗是全细胞百白破疫苗,发生率为284.74/10万。85.14%的AEFI发生于接种后的1d内,发生后≤1d就诊的占73.55%。12例异常反应有3例是由接种卡介苗引起的,均为淋巴结炎。[结论]泰安市AEFI监测系统运转良好。
[Objective] To understand the occurrence of various vaccination abnormalities in Tai’an in 2011 and evaluate the operational status of the surveillance system of suspected opportunistic immunization (AEFI) in Tai’an. [Method] A descriptive epidemiological analysis was conducted on cases of suspected abnormal immunization in 2011 in Tai’an City. [Results] AEFI was caused by 25 kinds of vaccines in Taian city in 2011, with a total of 276 cases. The reported incidence was 15.66 / 100000. In 276 cases, 94.93% of the general reactions, 4.35% of the abnormal reactions, 0.72% of the complications; 57.97% of males and 42.03% of females; 62.32% of children <1 year old. The most AEFI vaccine is the whole cell diphtheriae vaccine, the incidence was 284.74 / 100,000. 85.14% of AEFI occurred within 1d after inoculation, and 73.55% of patients were diagnosed ≤1d after the onset of AEFI. There were 3 cases of abnormal reaction in 12 cases caused by BCG vaccination, all of which were lymphadenitis. [Conclusion] The AEFI monitoring system in Tai’an is working well.