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目的:了解江苏省7岁以下儿童先天性和遗传性疾病发生情况。方法:对江苏省13个市的19个区(县)、110个乡镇(街道)26803例妇女于孕20～25周、婴儿出生时、子女3～4岁和6～7岁时开展先天性和遗传性疾病监测。结果:儿童胚胎发育阶段至出生时发现先天性和遗传性疾病发生率为111.18/万(298例);3～4岁发生率为134.68/万(361例);6～7岁发生率为203.34/万(545例)。患病数男童344例(63.12%),女童201例(36.88%)。乡镇发生率(229/万)高于城区(159/万)(P<0.001)。结论:先天性和遗传性疾病发生比例随着儿童的生长发育呈增高趋势,排列前几位疾病略有变化,应加强先天性和遗传性疾病多发地区一级预防工作。
Objective: To understand the incidence of congenital and hereditary diseases in children under 7 years of age in Jiangsu Province. Methods: 26803 women in 19 districts (counties) and 110 towns (streets) in 13 cities of Jiangsu Province were pregnant at 20-25 weeks, born at birth, children 3-4 years old and 6-7 years old. And genetic disease surveillance. Results: The incidence of congenital and hereditary diseases was 111.18 / 000 (298 cases) at the stage of embryonic development until birth, 134.68 / million (361 cases) at 3 to 4 years old, and 203.34 / Million (545 cases). 344 boys (63.12%) were affected and 201 girls (36.88%) were girls. The incidence of township (229 / 10,000) was higher than that of urban areas (159 / 10,000) (P <0.001). CONCLUSION: The proportion of congenital and hereditary diseases increases with the growth of children. The first few diseases are slightly changed. Prevention of primary prevention in congenital and hereditary diseases should be strengthened.